Pharmacological and Non-Pharmacological Recanalization Strategies in Acute Ischemic Stroke

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منابع مشابه

Pharmacological and Non-Pharmacological Recanalization Strategies in Acute Ischemic Stroke

According to the guidelines of the European Stroke Organization (ESO) and the American Stroke Association (ASA), acute stroke patients should be managed at stroke units that include well organized pre- and in-hospital care. In ischemic stroke the restoration of blood flow has to occur within a limited time window that is accomplished by fibrinolytic therapy. Newer generation thrombolytic agents...

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Recanalization Therapies in Acute Ischemic Stroke: Pharmacological Agents, Devices, and Combinations

The primary aim of thrombolysis in acute ischemic stroke is recanalization of an occluded intracranial artery. Recanalization is an important predictor of stroke outcome as timely restoration of regional cerebral perfusion helps salvage threatened ischemic tissue. At present, intravenously administered tissue plasminogen activator (IV-TPA) remains the only FDA-approved therapeutic agent for the...

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Pharmacological treatment of acute ischemic stroke.

Ischemic stroke is devastating. It is the third leading cause of death in the United States. Each year, 480,000 people fall victim to ischemic stroke, which is estimated to cost 71.8 billion dollars (Hinkle JL, Bowman L. J Neurol Nurs. 2003;35:1-8. New treatment is available. Acute ischemic stroke is no longer considered an accident resulting in damage that must simply be dealt with. Now termed...

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Recanalization and reperfusion in acute ischemic stroke

Revascularization remains the most intuitive strategy to reverse ischemic injury associated with arterial occlusion in acute stroke. Revascularization may lead to opening of an occluded artery, or recanalization, yet restoration of downstream flow, or reperfusion, may not ensue. Revascularization strategies and novel devices continue to broaden options for the treatment of acute stroke, but it ...

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Treatment of acute ischemic stroke: Part I: recanalization strategies.

59. Adams H Jr, Brott T, Furlan A, et al. Guidelines for thrombolytic therapy for acute stroke: a supplement to the guidelines for the management of patients with acute ischemic stroke (AHA Medical/Scientific Statement). Circulation. 1996;94:1167–1174. 60. Patel SC, Levine SR, Tilley BC, et al, for the National Institute of Neurological Disorders, and Stroke rt-PA Stroke Study Group. Lack of cl...

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ژورنال

عنوان ژورنال: Frontiers in Neurology

سال: 2011

ISSN: 1664-2295

DOI: 10.3389/fneur.2011.00032